Saikat Basu

Title

Assistant Professor

Office Building

Crothers Engineering Hall

Office

216

Mailing Address

Crothers Engineering Hall 216
Mechanical Engineering-Box 2219
University Station
Brookings, SD 57007

CV

Social Media Links

• LinkedIn

Education

• B.E. in civil engineering | Jadavpur University, India | 2009
• Ph.D. in engineering mechanics | Virgina Tech (2014)

Academic Interests

• Theoretical and computational fluid dynamics

Academic Responsibilities

• Engineering Mechanics in Biomedical Applications (ME 446/546, SDSU)
• Mechanical Design Technologies (ME 212, SDSU)
• Skeletal Biomechanics (Fall 2018, UNC Chapel Hill)
• Statics (Fall 2017, UNC Chapel Hill)
• Nonlinear Dynamics (Spring 2016, OIST Japan)
• Statics (Spring 2014, Virginia Tech)
• Fluid Mechanics I, II (Summer 2012, Virginia Tech)

Committees and Professional Memberships

Committees

• Member, NSF Grant Review Panels, 2020-Present
• Member, NIH Grant Review Panels, 2022-Present
• Member, SDSU College of Engineering Research Council, 2023-Present
• Member, SDSU Mechanical Engineering Faculty Search Committee, 2022-Present
• Faculty advisor, Biomedical Engineering Society (BMES) Chapter at SDSU, 2022-Present
• Member, SDSU Faculty Senate, 2019-2020
• Chair, Smithies Nobel Symposium Planning Sub-Committee, UNC Chapel Hill, 2017

Professional Memberships

• American Physical Society
• Biomedical Engineering Society
• International Society for Aerosols in Medicine

Awards and Honors

• 2024, ASME Rising Star of Mechanical Engineering
• 2024, NSF CAREER Award
• 2024, Outstanding Researcher Award, Jerome J. Lohr College of Engineering, South Dakota State University
• 2024, Faculty Award for International Research, Office of International Affairs, South Dakota State University
• 2023, Grantswinship Award, Jerome J. Lohr College of Engineering, South Dakota State University
• 2023, Early Career Investigator of the Year, Jerome J. Lohr College of Engineering, South Dakota State University
• 2018, Fluid Dynamics Research Prize, Japan Society of Fluid Mechanics
• 2015, Nomination for Outstanding Doctoral Dissertation, Virgina Tech
• 2013, Paul Torgersen Research Excellence Award
• 2010, Bechtel Travel Fellowship, Virginia Tech
• 2009, Pratt Presidential Graduate Fellowship, Virginia Tech
• 2008, Summer Fellowship, IASc India
• 2007, Summer Fellowship, JNCASR India
• 2004, National Merit Scholarship Certificate, India

Grants

• The Contagion Science: Integration of inhaled transport mechanics principles inside the human upper respiratory tract at multi scales. NSF CAREER Award, January 2024 - December 2028, $540,428.
• CAREER supplement : The Contagion Science: Integration of inhaled transport mechanics principles inside the human upper respiratory tract at multi scales. NSF Supplemental Award for Travel (an NSF - European Research Council Mechanism), January 2024 - December 2028, $17,058.
• Computational and theoretical fluid mechanics modeling for transport in dense tumors. NIH COBRE RPL Grant, March 2023, February 2026, $450,000.
• Sponsored collaboration with Aptar Pharma: Designing targeted carrier solutions for intranasal vaccines. Industry-Sponsored Project, August 2022 - May 2024, $66,066.
• Collaborative Research: New Generation of a Bio-inspired Protective Mask Based on Thermal and Vortex Traps. NSF CBET RAPID Grant, May 2020 - April 2022, $62,824.
• Computational tracking of perfusion in solid tumors. NIH COBRE Pilot Grant, April 2021 - July 2022, $49,999.
• Improving topical drug delivery for treatment of chronic rhinosinusitis using CFD, NIH R01 Subcontract from UNC Chapel Hill, April 2019 - May 2020, $20,021.
  Development of a digital platform to assess targeted regional drug delivery for airway sites. Haarberg Drug, Disease and Delivery (3D Center) Center Exploratory Grant, April 2023 - June 2024, $99,710.
• 'Peak band' vs. 'Monotonic decay': exploring particle deposition and penetration in anatomic cavities. Haarberg 3D Center Award for Undergraduate Research Support, February 2023 - June 2023, $3,000.
• Use of CFD to track respiratory transport in the throat. Scholarly Dissemination Award from SDSU Office of Academic Affairs, November 2019 - May 2020, $500.
• CFD-based identification of optimal particle sizes for targeted drug delivery at laryngeal granulomas. NIH NCATS Pilot Grant 2KR971701 awarded through UNC-CH, February 2018 - May 2019, $2,000.

Work Experience

• January 2019-present, assistant professor, tenure-track, South Dakota State University
• 2016-2018, postdoctoral fellow, UNC Chapel Hill
• 2017-2018, adjunct faculty, UNC/NC State University
• 2014-2016, postdoctoral scholar, OIST, Japan
• 2009-2014, graduate assistant, Virginia Tech
• 2008, summer intern: DLR, Braunschweig, Germany

Areas of Research

Bridging the ENG-MED disconnect through discoveries and extensions from classical fluid mechanics and biomathematical modeling, with core contributions in areas of airborne transmission of diseases through respiratory routes and cancer flow physics.

Publications

1. S Basu, LP Chamorro, M Yeasin, MA Stremler. Modeling the effect of vorticity on inhaled transport in the upper airway. arXiv: 2406.09708, under review, submitted 7/2024.
2. S Basu. On the mechanics of inhaled bronchial transmission of pathogenic microdroplets generated from the upper respiratory tract, with implications for infection onset. arXiv: 2406.17895, under review, submitted 6/2024.
3. Z Wu, S Basu, S Kim, M Sorrells, FJ Beron-Vera, S Jung. Coherent spore dispersion via drop-leaf interactions. Science Advances, Volume 10(5), eadj8092, 2024.
4. MMH Akash, Y Lao, PA Balivada, P Ato, NK Ka, A Mituniewicz, Z Silfen, J Suman, A Chakravarty, D Joseph-McCarthy, S Basu. On a model-based approach to improve intranasal spray targeting for respiratory viral infections. Frontiers in Drug Delivery, Sec. Respiratory Drug Delivery, Volume 3, 1164671, 2023.
5. MMH Akash, N Chakraborty, J Mohmmad, K Reindl, S Basu. Computational multiphase characterization of perfusion trends inside biomimetic reduced-order dense tumors. Experimental and Computational Multiphase Flow, Volume 5(3), 319-329, 2023.
6. J Yuk, MMH Akash, A Chakraborty, S Basu, LP Chamorro, S Jung. Morphology of pig nasal structure and modulation of airflow, thermal conditioning, and olfactory functionality. Integrative and Comparative Biology, Volume 63(2), 304-314, 2023.
7. DV Egeren, M Stoddard, A Malakar, D Ghosh, A Acharya, S Mainuddin, B Majumdar, D Luo, R Nolan, D Joseph-McCarthy, LF White, NS Hochberg, S Basu, A Chakravarty. No magic bullet: limiting in-school transmission in the face of variable SARS-CoV-2 viral loads. Frontiers in Public Health, Sec. Infectious Diseases: Epidemiology and Prevention, Volume 10, 941773, 2022.
8. S Basu, UA Khwaja, SAA Rizvi, MA Sanchez-Gonzalez, G Ferrer. Evaluation of Patient Experience for a Computationally-Guided Intranasal Spray Protocol to Augment Therapeutic Penetration: Implications for Effective Treatments for COVID-19, Rhinitis, and Sinusitis. Medical Research Archives, Volume 10(4), 2022.
9. J Yuk, A Chakraborty, S Cheng, CI Chung, A Jorgensen, S Basu*, LP Chamorro*, S Jung*. On the design of particle filters inspired by animal noses. Journal of The Royal Society Interface, Volume 19(188), 20210849 | * all corresponding authors, 2022.
10. S Basu, MMH Akash, NS Hochberg, BA Senior, D Joseph-McCarthy, A Chakravarty. From SARS-CoV-2 infection to COVID-19 morbidity: an in silico projection of virion flow rates to the lower airway via nasopharyngeal fluid boluses. Rhinology Online (open-access, peer-reviewed journal from European Rhinologic Society), Volume 5(5), 10-18, 2022.
11. S Basu. Computational characterization of inhaled droplet transport to the nasopharynx. Scientific Reports (open-access, peer-reviewed journal from Nature), Volume 11(1), 6652, 2021.
12. MA Stremler, S Basu, E Masroor. Streamline patterns in 2P vortex street equilibria. Journal of Fluid Mechanics, Volume 901 E2, 1-4, 2020.
13. S Basu, LT Holbrook, K Kudlaty, O Fasanmade, J Wu, A Burke, BW Langworthy, M Mamdani, Z Farzal, WD Bennett, JP Fine, BA Senior, AM Zanation, CS Ebert Jr., A Kimple, B Thorp, DO Frank-Ito, GJM Garcia, JS Kimbell. Numerical evaluation of spray position for improved nasal drug delivery. Scientific Reports (open-access, peer-reviewed journal from Nature), Volume 10(1), 10568, 2020.
14. S Treat, CS Ebert Jr., Z Farzal, S Basu, AM Zanation, BD Thorp, JS Kimbell, BA Senior, AJ Kimple
    Intranasal corticosteroids: patient administration angles and impact of education. Rhinology Online (open-access, peer-reviewed journal from European Rhinologic Society), Volume 3, 160-166, 2020.
15. BM Brandon, WH Stepp, S Basu, JS Kimbell, BA Senior, WW Shockley, J Madison Clark. Nasal airflow changes with bioabsorbable implant, butterfly and spreader grafts. The Laryngoscope, Volume 130(12), E817-E823, 2020.
16. Z Farzal, S Basu, A Burke, O Fasanmade, E Mamuyac, W Bennett, CS Ebert Jr., A Zanation, BA Senior, JS Kimbell. Comparative study of simulated nebulized and spray particle deposition in chronic rhinosinusitis patients. International Forum of Allergy and Rhinology,  Volume 9(7), 746-758, 2019.
17. LF Tracy, S Basu, P Shah, DO Frank-Ito, S Das, A Zanation, JS Kimbell. Impact of endoscopic craniofacial resection on simulated nasal airflow and heat transport. International Forum of Allergy and Rhinology, Volume 9(8), 900-909, 2019

Working preprints

1. S Basu, A Malakar, MMH Akash. A mechanistic model for smallpox transmission via inhaled aerosols inside respiratory pathways. arXiv, DOI: 10.48550/arXiv.2403.04064, uploaded 2024 [pdf].
2. ML Tesch, A Malakar, SAA Rizvi, MMH Akash, G Ferrer, S Basu. Enhancing intranasal therapeutic penetration for treating respiratory illness: A clinical human factor feasibility study. Preprints.org, DOI: 10.20944/preprints202312.1002.v1, uploaded 2023 [pdf].
3. S Basu. Approaching Fermat's Conjecture from the Principle of Mathematical Induction
   Logic and Philosophy of Mathematics eJournal, SSRN 4023652, uploaded 2022 [pdf].
4. S Das and S Basu. On a model-based analysis of vortex formations and decay in flows through bio-inspired T-shaped cavities. arXiv, DOI: 10.48550/arXiv.2211.06964, uploaded 2022 [pdf].

Prior to SDSU

1. JS Kimbell, S Basu, GJM Garcia, DO Frank-Ito, FB Lazarow, E Su, DE Protsenko, Z Chen, J Rhee, BJ Wong. Upper airway reconstruction using anatomic optical coherence tomography: effects of airway bend on airflow resistance. Lasers in Surgery and Medicine, Volume 51(2), 150-160, 2019.
2. S Basu, DO Frank-Ito, JS Kimbell. On computational fluid dynamics models for sinonasal drug transport: relevance of nozzle subtraction and nasal vestibular dilation. International Journal for Numerical Methods in Biomedical Engineering, Volume 34(4), e2946, 2018.
3. E Perkins, S Basu, GJM Garcia, R Buckmire, R Shah, JS Kimbell. Ideal particle sizes for inhaled steroids targeting vocal granulomas: preliminary study using computational fluid dynamics. Otolaryngology – Head and Neck Surgery, Volume 158(3), 511-519, 2018.
4. BM Brandon, GK Austin, G Fleischman, S Basu, JS Kimbell, WD Shockley, J Madison Clark. Comparison of airflow between spreader and butterfly grafts using computational fluid dynamics in cadaveric models. JAMA Facial Plastic Surgery, Volume 20(3), 215-221, 2018.
5. JS Kimbell, S Basu, Z Farzal, BA Senior. Characterizing nasal delivery in 3D models before and after sinus surgery. Respiratory Drug Delivery, Volume 1, 181-188, 2018.
6. S Basu, A Yawar, A Concha, MM Bandi. On angled bounce-off impact of a drop impinging on a flowing soap film. Fluid Dynamics Research, Volume 49(6), 065509, 2017 | Awarded Fluid Dynamics Research Prize 2018.
7. S Basu and MA Stremler. Exploring the dynamics of 2P wakes with reflective symmetry using point vortices. Journal of Fluid Mechanics, Volume 831, 72-100, 2017.
8. S Basu and MA Stremler. On the motion of two point vortex pairs with wake-inspired glide-reflective symmetry in a periodic strip. Physics of Fluids, Volume 27(10), 103603, 2015.
9. MA Stremler and S Basu. On point vortex models of exotic bluff body wakes. Fluid Dynamics Research, Volume 46(6), 061410, 2014.
10. MA Stremler, A Salmanzadeh, S Basu, CHK Williamson. A mathematical model of 2P and 2C vortex wakes. Journal of Fluids and Structures, Volume 27(5-6),  774-783, 2011.

Working preprint

1. SB Sreenath, JS Kimbell, S Basu, AJ Coniglio, TE Fontenot, BD Thorp, CS Ebert, BA Senior, AM Zanation. Comparative Analysis of the Main Nasal Cavity and the Paranasal Sinuses in Chronic Rhinosinusitis: An Anatomic Study of Maximal Medical Therapy. arXiv, DOI: 10.48550/arXiv.1811.00649, uploaded 2018